Clinical Studies

Journal of Clinical and Aesthetic Dermatology

Objective

Evaluation of the PRO Rebalancing Lotion in the reduction of facial erythema following a chemical peel treatment. Edema was also assessed.

Source: Journal of Clinical and Aesthetic Dermatology October 2016 JClin Aesthet Dermatol. 2016; 9(10):55-62

Title: A Split-Face Evaluation to Assess the Efficacy of a Hydrolyzed Roe Cream in Reduction of Erythema Following Chemical Peel

Design

The PRO Rebalancing Lotion was applied to one side of the face of 30 healthy female subjects (average age=54.9 years, range 33-65 years) immediately following 4 to 15 minutes peel treatment. The opposite side remained untreated. Visia-CR digital photographs were taken at baseline and 8 and 24 hours post-facial peel. Objective dermal irritation assessments were done by a blinded investigator, graded on severity of facial erythema and edema on a 5-point scale; 0=none, 1=slight, 2=mild, 3=moderate, 4=severe. Subjects completed a perception questionnaire.

Results

Reduction in erythema was greater (P less than or equal to: 0.05) for the treated side of the face compared to the untreated side at both 8 and 24 hours post-peel. Both sides showed reduction in erythema compared to immediate post-peel. No edema was observed. At eight hours, more than 50% of subjects agreed on the five attributes, and at 24 hours, 57% (17/30) of subjects agreed. At eight hours, greater than or equal to 80 percent of subjects strongly agreed or agreed that the treated skin feels hydrated and moisturized immediately after application. At 24 hours, more than 90 percent of subjects strongly agreed or agreed that treated skin feels perfectly hydrated and moisturized. When asked about their overall impression of the product, 60 percent (18 subjects) of subjects responded said, “I love it.” All subjects completed the study. No adverse events were reported.

Journal of Drugs in Dermatology

Results

Topical hydrolyzed roe protean used twice daily improves skin clarity. It has good tolerability with fewer instances of stinging and burning than other glycolic acid containing cream. Patient's opinions of the 3 products were similar.

Newsletter: November 14, 2022
Date: October 25, 2022
Title: How to Order Restorsea PRO Products

As you know, I try my best to personally answer all of your emails. The most frequently asked question is, “How do I order PRO products?

The RestorseaPRO website is for information purposes only. This is why when you click on the product section, you are unable to make a purchase.

In order to purchase, you need to go to the physician locator page, type in your zip code and click on the physician’s name. It will then provide you with their address and phone number and their purchase link. If you click on the purchase link, you will be taken to their custom Restorsea PRO microsite. This will enable you to purchase ANY Restorsea or Restorsea PRO product.

The reason why the PRO products are so difficult to purchase is by choice. We wanted the PRO products to be sold by the leading dermatologist/surgeons and skincare providers. And, of these top providers, we wanted their offices to be committed to partnering with Restorsea to build a lasting and substantial business.

When we launched in physician’s offices, we were expressly told by them that we needed to make the PRO products exclusive to this channel. The physician said it was very frustrating to spend time with their patients to explain a skincare product only to have their patient purchase it somewhere else. So, if we wanted to sell Restorsea PRO in their offices, we needed to sell only in their respective offices.

COVID-19 changed this equation slightly. The world in the U.S. shut down on March 20, 2020. On March 23, 2020, I received over 100 emails from the doctors’ patients asking if they could purchase the PRO products directly from Restorsea as their respective physician’s office was closed.

Our response was to create the PRO Direct program. We created unique Restorsea microsites; one for each PRO MD account. Every patient/customer who wrote to us received their physician’s Restorsea microsite. Every time the patient clicked on their PRO MD’s microsite, it was a win-win-win situation. The patient received their product, the associated PRO MD received their commission and Restorsea was able to fulfill the PRO product orders.

Restorsea started as a department store business as we launched in Bergdorf Goodman. I was honestly so happy at getting distribution, I didn’t stop to think if this was the right channel.
While we were successful and enjoyed selling in Bergdorf Goodman, we couldn’t figure out how to make the business profitable.

We created the PRO line because it enabled us to differentiate ourselves in a very crowded and competitive market. The PRO line is the ONLY clean physician-dispensed line backed by peer-reviewed clinical studies.

The difference between the PRO line and the regular line is that the PRO line products were formulated to help alleviate the symptoms caused by chronic skin conditions such as eczema, rosacea, acne and hyperpigmentation. Also, the products often contain higher percentages of the hatching enzyme, Aquabeautine XL®*. Full disclosure: I use the Rejuvenating Day Cream. My mom, Joanne says that it is the “Windex of Skincare…”

I am very grateful to the Restorsea PRO MDs because they validated and spread the word about our unique, innovative and efficacious technology. And I am thankful and grateful to all of YOU for your support (many from the Company’s inception).

The main lesson I have learned from this experience is that you MUST have the right route to market. No matter how great your product is, if it is not in the right distribution channel, it is not going to be successful.

Just some food for thought.
Wishing everyone a great week.

XOX, Patti